![]() Furthermore, extracts of the ZnCuFe (0.2 wt%) alloy showed no apparent cytotoxic effects against L929 fibroblasts, Saos-2 osteoblasts or TAg periosteal cells. The ZnCuFe (0.2 wt%) alloy showed relatively uniform corrosion in the long-term degradation test. Moreover, the addition of Fe successfully accelerated the degradation of ZnCuFe alloys. Since elongation declined significantly until fracture with increasing Fe content up to 0.4 wt%, the ZnCuFe (0.2 wt%) alloy achieved a good balance between mechanical strength and ductility, with an ultimate tensile strength of 202.3 MPa and elongation at fracture of 41.2%. ![]() With increasing Fe content, a higher FeZn 13 phase precipitation with larger particles was observed. The ZnCuFe alloys were composed of a Zn matrix and FeZn 13 phase. The microstructure, mechanical properties and in vitro degradation behavior were systematically investigated. ![]() The hot-extrusion process and Cu alloying were expected mostly to enhance the mechanical properties, and the Fe alloying was added mainly for regulating the degradation. In this study, hot-extruded Zn–0.5Cu–xFe (x = 0.1, 0.2 and 0.4 wt%) alloys were fabricated as candidates for biodegradable materials for guided bone regeneration (GBR) membranes. Appropriately adapted comprehensive mechanical properties, degradation behavior and biocompatibility are prerequisites for the application of Zn-based biodegradable implants. ![]()
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